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HIV Viral Load Suppression Status and Associated Factors Among Patient Under ART in Ethiopia, 2016

Description

Id	EPHI-DS0086
Name	HIV Viral Load Suppression Status and Associated Factors Among Patient Under ART in Ethiopia, 2016
Format	.xlsx
Coverage Location	Subnational
Coverage Sex	Both
Abstract	In Ethiopia, immunologic and clinical parameters have been used to monitor HIV patients on ART. Recently the government has implemented viral load (VL) testing in multiple testing centers across the regions; however, the viral suppression rate is not well studied. The aim of this study was, therefore, to determine the level of viral suppression and associated factors among HIV patients on active ART. This study used routine VL program data of 8,389 adults and children, measured for patient clinical monitoring at Ethiopian public health institute, HIV national reference laboratory. The laboratory received a biological sample (Plasma, whole blood, or dried blood spot) to determine the viral load from 70 health facilities referral linkage. The laboratory diagnostic result was entered into a database built for this purpose on daily basis by a trained data clerk. The duration of the client on ART was at least six months at the time of viral load measurement. The main outcome variable of the study was VL measured by Abbott Real-Time and Cobas Ampliprep/Cobas Taqman platforms. Socio-demographics and baseline clinical characteristics were used as exposure variables. multivariable regression analysis was employed to identify the associated factors with high viral load. A P-value less than 0.05 was used to declare the statistical significance. The results of the study showed that: 1) Of the participants 5,038(60%) were female, 1,136 (13.6%) were children (less than 15). 2) The overall viral load suppression (HIV RNA copies<1000 copies/ml) was found to be 86%. 3) The VL suppression was not significantly different between the two genders. 4) Advanced WHO clinical stage and poor adherence were significantly associated with impaired virologic suppression. In conclusion, the study showed generally sub-optimal viral suppression among patients under ART which might pose a question on the success of ART programs in Ethiopia. This finding would supplement to serve as the evidence for tracking the progress towards the third of the 90-90-90 UNAIDS ambitious plan.
Additional Material	No
Keywords	retrospective-cross-sectional survey adults and children HIV Antiretroviral drugs viral load viral suppression Health facilities
Recommended	Yes
Location
Cleaned	Yes
Cleaned Format	. csdb
RawFormat	. csdb
Comment
Remark
Note
Treatment
Date Data Collection Started	2016-03-01
Date Data Collection End	2016-05-30
Title	HIV Viral Load Suppression Status and Associated Factors Among Patient Under ART in Ethiopia, 2016
Data Type	Survey
PublicationYear	2017
SugestedCitation	There is no Suggested citation by the publisher or producer of a dataset
OtherIdType
Description	This dataset is produced by a retrospective cross-sectional study that was conducted among HIV patients on ART whose VL determined at EPHI in 2016. The dataset captures Socio-demographic and related information including reason for Test (Suspected ART Failure, First RVLM/ 6th month, RVLM 12th month), Adherence (poor, fair, good), Baseline CD4, Most Recent CD4, Treatment, Brest Feeding, age, sex, region of the study participants. The dataset also includes information on Viral Load measured by Abbott Real-Time and Cobas Ampliprep/Cobas Taqman platforms. Thus, the dataset is used to analyze the level of viral suppression and associated factors among HIV patients on active ART collected from different health facilities.
Dataset study design	Experimental study
Date Data Archived	2019-09-30
Date Data Cataloged	2020-05-18
Data Generating Unit	HIV and TB Research Directorate
URL	https://rtds.ephi.gov.et/public/showdetail/86
Tags

Unpublished

Open Access