H-DAV NDMC EPHI

HIV-1 Treatment Failure among Population Taking Antiretroviral Therapy in Ethiopia, 2017


Description
Id EPHI-DS0340
Name HIV-1 Treatment Failure among Population Taking Antiretroviral Therapy in Ethiopia, 2017
Format . SAV
Coverage Location National
Coverage Sex Both
Abstract

The study was conducted from March 2016 to 2017. Retrospective clinical and laboratory data were captured from patients’ medical records. Socio-demographics and explanatory variables of participants were collected using a pre-tested structured questionnaire and study participants were followed for an additional 6 months after baseline viral load has been done to classify virologic failure (VF). Multiple logistic regression was conducted to assess risk factors associated with TF. Statistical significance was set at P-value less than 0.05. A total of 9,284 adults taking ART from a nationally representative 63 health facilities were included in the study. Viral Load Suppression (VLS) (VL<1000 copies/ml) among the population taking HAART in Ethiopia was found to be 8,180 (88.1%). Thirty-five percent of the study participants with VL>1000 copies/ml at baseline of the study were re-suppressed after six months of enhanced adherence and counseling, leading TF among the population on ART in Ethiopia to be 983 (11%). Immunologic and clinical failure was significantly improved from 21.5% and 16.5% at ART initiation to 576 (6.2%) and 470 (5.0%) at baseline of the study, respectively. Medication adherence, disclosure of HIV status, missed appointment to ART, history of ART exposure prior to initiation, residency and marital status had a significant association with TF.

Additional Material No
Keywords
  • Antiretroviral therapy
  • Treatment failure
  • Viral suppression
  • Adherence
  • Ethiopia
Recommended Yes
Location
Cleaned No
Cleaned Format . csdb
RawFormat . csdb
Comment
Remark
Note
Treatment
Date Data Collection Started 2016-03-01
Date Data Collection End 2017-03-30
Title HIV-1 Treatment Failure among Population Taking Antiretroviral Therapy in Ethiopia, 2017
Data Type Survey
PublicationYear 2000
SugestedCitation

no

OtherIdType
Description

A prospective and retrospective study was conducted from March 2016 to 2017. Retrospective clinical and laboratory data were captured from patients’ medical records. Socio-demographics and explanatory variables of participants were collected using a pre-tested structured questionnaire and study participants were followed for an additional 6 months after baseline viral load has been done to classify virologic failure (VF). Multiple logistic regression was conducted to assess risk factors associated with TF. Statistical significance was set at P-value less than 0.05.

Dataset study design Surveillance
Date Data Archived 2020-01-01
Date Data Cataloged 2021-10-23
Data Generating Unit Ethiopian Public Health Institute (EPHI)
URL https://rtds.ephi.gov.et/public/showdetail/340

Tags
Unpublished

Open Access