The HIV  incidence study under the survey of the EPHIA conducted among the 19133 adult urban populations to estimate the incidence of HIV. The survey used a two-stage, stratified cluster sample design, in which census enumeration areas (EA) (clusters) were selected in the first stage and households in the second stage. The sample was stratified by nine regional states and two city administrations: Tigray, Afar, Amhara, Oromia, Ethiopian Somali, Benishangul Gumuz, SNNPR, Gambella, Harari, Addis Ababa, and Dire Dawa. Data collection was conducted from the beginning of October 2017 to the end of April 2018. EPHIA provided home-based testing and counseling (HBTC) with the return of results and point-of-care (POC) CD4 counts for those who were HIV positive. This study presents annual estimates of HIV incidence in 2017-2018 among adults in urban areas at the national level. For the purposes of this analysis, HIV incidence is expressed as the cumulative incidence or risk of new infections in a 12-month period, which is a close approximation to the instantaneous incidence rate. It is important to note that the EPHIA primary objective was to estimate the prevalence of viral load suppression, to which the sample size was powered. Two laboratory-based incidence testing algorithms (HIV-1 LAg avidity plus viral load and HIV-1 LAg avidity plus viral load and ARV detection) were used to distinguish recent from long-term infection. Incidence estimates have obtained the formula recommended by the WHO Incidence Working Group and Consortium for Evaluation and Performance of Incidence Assays, and with assay performance characteristics of a mean duration of recent infection (MDRI)=130 days (95% CI: 118, 142), with time cutoff (T)=1.0 year and residual proportion false recent (PFR)=0.00. Survey weights are utilized for all estimates. All HIV-positive participants 18 months and older were tested for recent infection using HIV-1 LAg avidity assay. The incidence of HIV infection in 2017-2018 among adults (ages 15-64 years) in urban Ethiopia was 0.05%. This corresponds to approximately 6,000 new cases of HIV among adults living in urban Ethiopia.

• Incidence
• HIV infection
• HIV test
• Household
• Adult
• Urban
• Ethiopia
• cross sectional
• VL
• HIV prevalence

Ethiopian Public Health Institute (EPHI).
 Ethiopia Population-Based HIV Impact Assessment (EPHIA) 2017-2018: 
Final Report. Addis Ababa, EPHI. December, 2019.

The HIV incidence data set is a cross-sectional study conducted among the urban population in Ethiopia. The survey used a two-stage, stratified cluster sample design, in which census enumeration areas (EA) (clusters) were selected in the first stage and households in the second stage. The sample was stratified with nine regional states and two city administrations: Tigray, Afar, Amhara, Oromia, Ethiopian Somali, Benishangul Gumuz, SNNPR, Gambella, Harari, Addis Ababa, and Dire Dawa. In that regard, the data collection was conducted from the beginning of October 2017 to the end of April 2018. EPHIA provided home-based testing and counseling (HBTC) with the return of results and point-of-care (POC) CD4 counts for those who were HIV positive. The study includes 19133 adults and 10529 households. In this incidence study, Two laboratory-based incidence testing algorithms (HIV-1 LAg avidity plus viral load and HIV-1 LAg avidity plus viral load and ARV detection) were used to distinguish recent from long-term infection. Incidence estimates have obtained the formula recommended by the WHO Incidence Working Group and Consortium for Evaluation and Performance of Incidence Assays, and with assay performance characteristics of a mean duration of recent infection (MDRI)=130 days (95% CI: 118, 142), with time cutoff (T)=1.0 year and residual proportion false recent (PFR)=0.00. Survey weights are utilized for all estimates. All HIV-positive participants 18 months and older were tested for recent infection using HIV-1 LAg avidity assay. Incidence estimation is based on recent/long-term (LT) classification using algorithms with limiting antigen (LAg) avidity. Based upon the ARV-adjusted incidence, approximately 6,000 new HIV infections occurred annually in urban Ethiopia at the time of the survey. 

Copy url