Immuno-haematological reference ranges for adult Ethiopians
| Id | EPHI-DS0119 |
|---|---|
| Name | Immuno-haematological reference ranges for adult Ethiopians |
| Format | .dta |
| Coverage Location | National |
| Coverage Sex | Both |
| Abstract | The study on immuno-hematological reference ranges for adult Ethiopians aimed to establish Immunohematological reference values which may serve as Ethiopian standards for the interpretation of laboratory results A cross-sectional survey was carried out with738 adult Ethiopians who are participating in a cohort study on the progression of human immunodeficiency virus type 1 (HIV-1) infection to establish hematological reference ranges fur adult HIV-negative Ethiopians. In addition, enumeration of absolute numbers and percentages of leukocyte subsets was performed for 142 randomly selected HIV-negative individuals. Immunological results were compared to those of 1,356 healthy HIV-negative Dutch blood donor controls. Immunohematological mean values, medians, and 95th percentile reference ranges were established. In that regard, the data were entered and analyzed with the Dbasel!]+ and STATA programs, respectively. Mean, median, and standard deviation were calculated for each Immunohematological parameter. The nonparametric Wilcoxon rank-sum test (Mann-Whitney U test) was used to compare the distribution of Immunohematological parameters between genders. In conclusion, the WBC and platelet values of healthy HIV-negative Ethiopians are lower than the adopted reference values of Ethiopia, the absolute CD4 T-cell counts of healthy HIV-negative Ethiopians are considerably lower than those of the Dutch controls, while the opposite is true for the absolute CDS T-cell counts. This results in a significantly reduced CD4/CDS T-cell ratio for healthy Ethiopians, compared to the ratio for Dutch controls. |
| Additional Material | No |
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| Recommended | Yes |
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| Cleaned | Yes |
| Cleaned Format | . csdb |
| RawFormat | . csdb |
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| Date Data Collection Started | 1997-01-01 |
| Date Data Collection End | 1997-04-30 |
| Title | Immunohaematologicall reference ranges for adult Ethiopians |
| Data Type | Survey |
| PublicationYear | 1999 |
| SugestedCitation | No suggested citation |
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| Description | The study on Immunohaematologicall reference ranges for adult Ethiopians is a cross-sectional survey conducted in Addis Ababa and wonji Factory workers of 738 participants to establish imuno-hematological reference values for adult Ethiopians. enumeration of absolute numbers and percentages of leukocyte subsets was performed for 142 randomly selected HIV-negative individuals. In that regard, immunological results were compared to those of 1,356 healthy HIV-negative Dutch blood donor controls. Immunohematological mean values, medians, and 95th percentile reference ranges were established. Besides. whole blood was collected with a Vacationer system in 10-ml lubes containing EDTA, HIV status was determined with plasma samples by an enzyme-linked immunosorbent assay with a Vimnostika HIV Uni-Ftirm 11 plus O kit (Organon Teknika. Boxtel. The Netherlands). Finally, positive results were confirmed by western blot analysis. |
| Dataset study design | Longitudinal |
| Date Data Archived | 2020-08-15 |
| Date Data Cataloged | 2020-08-31 |
| Data Generating Unit | Ethiopian Public Health Institute (EPHI) |
| URL | https://rtds.ephi.gov.et/public/showdetail/119 |
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Open Access