Low Baseline CD4 counts do not lead to faster HIV disease progression among Ethiopians
| Id | EPHI-DS0117 |
|---|---|
| Name | Low Baseline CD4 counts do not lead to faster HIV disease progression among Ethiopians |
| Format | .dta |
| Coverage Location | National |
| Coverage Sex | Both |
| Abstract | The study was conducted in Akaki and Wonji factory workers Ethiopians the year from February 1997 to June 2002. The study aimed to estimate the survival time of HIV-infected Ethiopians, and compare the rate of CD4 count decline among Ethiopians and Dutch individuals. Among cohort studies participated in Akaki and Wonji 149 participants were included in this study. The survival time of the HIV-infected Ethiopians was estimated using the Markov model with CD4 count and WHO clinical staging. The decline rate of the CD4 count of HIV-infected Ethiopians was compared with Dutch homosexual men and drug users. In this Study the CD4 count, WHO clinical stage and socio-demographic characteristics, the survival time estimation were analyzed. This cohort study estimated a median survival time in the range of 9.1 to 12.8 years using different approaches. The rate of CD4 decline was significantly lower in Ethiopians compared to Dutch homosexual men and drug users. Although those homosexual men and drug users who had no evidence of Sl-inducing strains have a lower rate of CD4 decline than those who had Sl-inducing strains, they still have a significantly higher rate of CD4 decline than Ethiopians. The study concluded that low baseline CD4 counts among Ethiopians do not imply shorter HIV survival time than other populations and survival time in HIV-infected Ethiopians is similar to that of populations in industrialized countries before the advent of antiretroviral therapy. |
| Additional Material | No |
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| Recommended | Yes |
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| Cleaned | Yes |
| Cleaned Format | . csdb |
| RawFormat | . csdb |
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| Date Data Collection Started | 1997-02-01 |
| Date Data Collection End | 2002-06-30 |
| Title | Low Baseline CD4 counts do not lead to faster HIV disease progression in Ethiopians |
| Data Type | Survey |
| PublicationYear | 2005 |
| SugestedCitation | no suggested citation
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| Description | The low CD4 count and disease progression study among HIV-infected Ethiopians is primarily aimed to estimate the survival time of the HIV-infected individuals and to compare the rate of CD4 count decline among Ethiopians and Dutch homosexual men and drug users. The study clearly answers whether low baseline CD4 count influences the survival time and disease progression of HIV-infected Ethiopians. The sampling method of this study was a national representative and cohort study design used to address the study participants. |
| Dataset study design | Clinical trials |
| Date Data Archived | 2020-08-15 |
| Date Data Cataloged | 2020-08-27 |
| Data Generating Unit | Ethiopian Public Health Institute (EPHI) |
| URL | https://rtds.ephi.gov.et/public/showdetail/117 |
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Open Access